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Upingbio
SKU:YP-Ab-01865-100UL
MEF-2B Polyclonal Antibody
MEF-2B Polyclonal Antibody
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- Gene Name: MEF2B
- Immunogen: The antiserum was produced against synthesized peptide derived from human MEF2B. AA range:51-100
- Specificity: MEF-2B Polyclonal Antibody detects endogenous levels of MEF-2B protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: MEF2B; XMEF2; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2
- Background: This gene represents numerous read-through transcripts that span GeneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on GeneID:100271849. [provided by RefSeq, Oct 2010],
- Function: function:Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.,similarity:Belongs to the MEF2 family.,similarity:Contains 1 MADS-box domain.,similarity:Contains 1 Mef2-type DNA-binding domain.,subunit:Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.,tissue specificity:Expressed in skeletal and cardiac muscle and brain.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: Myocyte-specific enhancer factor 2B
- DA: 38kD
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