• CNOT4 Polyclonal Antibody
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Upingbio

YP-Ab-01616-100UL

CNOT4 Polyclonal Antibody

CNOT4 Polyclonal Antibody

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  • Gene Name: CNOT4
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CNOT4. AA range:61-110
  • Specificity: CNOT4 Polyclonal Antibody detects endogenous levels of CNOT4 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CNOT4; NOT4; CCR4-NOT transcription complex subunit 4; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; Potential transcriptional repressor NOT4Hp
  • Background: CCR4-NOT transcription complex subunit 4(CNOT4) Homo sapiens The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010],
  • Function: function:Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Sequencing errors.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Subunit of the CCR4-NOT core complex that contains CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6 and CNOT8. Binds CNOT1 via its C-terminus. Binds E2 ubiquitin ligases via its RING domain.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: CCR4-NOT transcription complex subunit 4
  • DA: 64kD
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