• CGGBP1 Polyclonal Antibody
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Upingbio

YP-Ab-01607-100UL

CGGBP1 Polyclonal Antibody

CGGBP1 Polyclonal Antibody

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  • Gene Name: CGGBP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CGGBP1. AA range:41-90
  • Specificity: CGGBP1 Polyclonal Antibody detects endogenous levels of CGGBP1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CGGBP1; CGGBP; CGG triplet repeat-binding protein 1; CGG-binding protein 1; 20 kDa CGG-binding protein; p20-CGGBP DNA-binding protein
  • Background: CGGBP1 influences expression of the FMR1 gene (MIM 309550), which is associated with the fragile X mental retardation syndrome (MIM 300624), by specifically interacting with the 5-prime (CGG)n-3-prime repeat in its 5-prime UTR.[supplied by OMIM, Mar 2008],
  • Function: developmental stage:Expressed in fetal brain and kidney. Lower expression in fetal liver and lung.,function:Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.,miscellaneous:Binding is severely inhibited by complete or partial cytosine-specific DNA methylation of the binding motif.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain.,
  • Species: Human;Mouse
  • Range: IHC;IF;ELISA
  • Protein: CGG triplet repeat-binding protein 1
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