• CDK5 Activator-binding C42 Polyclonal Antibody
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YP-Ab-01601-100UL

CDK5 Activator-binding C42 Polyclonal Antibody

CDK5 Activator-binding C42 Polyclonal Antibody

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  • Gene Name: CDK5RAP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CDK5RAP1. AA range:251-300
  • Specificity: CDK5 Activator-binding C42 Polyclonal Antibody detects endogenous levels of CDK5 Activator-binding C42 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CDK5RAP1; C20orf34; CGI-05; HSPC167; CDK5 regulatory subunit-associated protein 1; CDK5 activator-binding protein C42
  • Background: This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013],
  • Function: cofactor:Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.,function:Specifically inhibits CDK5 activation by CDK5R1.,sequence caution:Translated as Glu.,similarity:Belongs to the methylthiotransferase family. MiaB subfamily.,similarity:Contains 1 MTTase N-terminal domain.,similarity:Contains 1 TRAM domain.,subunit:Interacts with CDK5R1 (p35 form). CDK5RAP1, CDK5RAP2 and CDK5RAP3 show competitive binding to CDK5R1. Forms a complex with CDK5R1 and CDK5.,tissue specificity:Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
  • Species: Human;Rat;Mouse;
  • Range: IHC;IF;ELISA
  • Protein: CDK5 regulatory subunit-associated protein 1
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