• CBP80 Polyclonal Antibody
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Upingbio

YP-Ab-01591-100UL

CBP80 Polyclonal Antibody

CBP80 Polyclonal Antibody

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  • Gene Name: NCBP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human NCBP1. AA range:1-50
  • Specificity: CBP80 Polyclonal Antibody detects endogenous levels of CBP80 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: NCBP1; CBP80; NCBP; Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunit
  • Background: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008],
  • Function: function:Involved in mediating U snRNA export from the nucleus. Binds to 5' capped mRNA.,similarity:Belongs to the NCBP1 family.,similarity:Contains 1 MIF4G domain.,subunit:Found in a U snRNA export complex with RNUXA/PHAX, CBP20, CBP80, RAN, XPO1 and m7G-capped RNA. Interaction with RNUXA/PHAX (By similarity). Heterodimer with NCBP2. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2, THOC4 and/or REFBP2.,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Nuclear cap-binding protein subunit 1
  • DA: 80kD
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