• Bcl-7a Polyclonal Antibody
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Upingbio

YP-Ab-01566-100UL

Bcl-7a Polyclonal Antibody

Bcl-7a Polyclonal Antibody

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  • Gene Name: BCL7A
  • Immunogen: The antiserum was produced against synthesized peptide derived from human BCL7A. AA range:21-70
  • Specificity: Bcl-7a Polyclonal Antibody detects endogenous levels of Bcl-7a protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: BCL7A; B-cell CLL/lymphoma 7 protein family member A
  • Background: This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • Function: disease:Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the BCL7 family.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: B-cell CLL/lymphoma 7 protein family member A
  • DA: 22kD
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