• AF-10 Polyclonal Antibody
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Upingbio

YP-Ab-01521-100UL

AF-10 Polyclonal Antibody

AF-10 Polyclonal Antibody

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  • Gene Name: MLLT10
  • Immunogen: The antiserum was produced against synthesized peptide derived from human AF10. AA range:211-260
  • Specificity: AF-10 Polyclonal Antibody detects endogenous levels of AF-10 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein
  • Background: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10(MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010],
  • Function: disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein.,disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PHD-type zinc fingers.,tissue specificity:Expressed abundantly in testis.,
  • Species: Human;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Protein AF-10
  • DA: 109kD
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