• YAP (phospho-Ser397) rabbit pAb
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YP-Ab-01483-100UL

YAP (phospho-Ser397) rabbit pAb

YAP (phospho-Ser397) rabbit pAb

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  • Gene Name: YAP1 YAP65
  • Immunogen: Synthesized phosho peptide around human YAP (Ser397)
  • Specificity: This antibody detects endogenous levels of Human Mouse Rat YAP (phospho-Ser397)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Yorkie homolog (65 kDa Yes-associated protein) (YAP65)
  • Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],
  • Function: PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 WW domain.,subunit:Binds to the SH3 domain of the YES kinase. Binds to WBP1 and WBP2. Binds, in vitro, through the WW1 domain, to neural isoforms of ENAH that contain the PPSY motif.,
  • Species: Human;Mouse;Rat
  • Range: WB
  • Protein: YAP (Ser397)
  • DA: 67kD
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