• TORC1/CRTC1 (phospho-Ser151) rabbit pAb
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Upingbio

YP-Ab-01480-100UL

TORC1/CRTC1 (phospho-Ser151) rabbit pAb

TORC1/CRTC1 (phospho-Ser151) rabbit pAb

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  • Gene Name: CRTC1 KIAA0616 MECT1 TORC1 WAMTP1
  • Immunogen: Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)
  • Specificity: This antibody detects endogenous levels of Human TORC1 or CRTC1 (phospho-Ser151)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)
  • Function: disease:A chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11;19)(q21;p13) with MAML2. The fusion protein consists of the N-terminus of CRTC1 joined to the C-terminus of MAML2. The reciprocal fusion protein consisting of the N-terminus of MAML2 joined to the C-terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator
  • Species: Human;Rat;Mouse;
  • Range: WB
  • Protein: TORC1/CRTC1 (Ser151)
  • DA: 70kD
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