• RPA32/RPA2 (phospho-Ser8) rabbit pAb
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Upingbio

YP-Ab-01462-100UL

RPA32/RPA2 (phospho-Ser8) rabbit pAb

RPA32/RPA2 (phospho-Ser8) rabbit pAb

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  • Gene Name: RPA2 REPA2 RPA32 RPA34
  • Immunogen: Synthesized phosho peptide around human RPA32 and RPA2 (Ser8)
  • Specificity: This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
  • Function: function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
  • Species: Human;Rat;Mouse;
  • Range: WB
  • Protein: RPA32/RPA2 (Ser8)
  • DA: 32kD
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