• MICU1 Monoclonal Antibody(Mix)
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Upingbio

YP-Ab-01144-53UL

MICU1 Monoclonal Antibody(Mix)

MICU1 Monoclonal Antibody(Mix)

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  • Reaction species: Human;Mouse;Rat
  • Gene Name: MICU1
  • Protein name: Calcium uptake protein 1, mitochondrial
  • Molecular weight (DA): 55kD
  • Immunogen: Recombinant Protein of MICU1
  • Specificity: The antibody detects endogenous MICU1 protein.
  • Composition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: Calcium uptake protein 1, mitochondrial; Atopy-related autoantigen CALC; ara CALC; Calcium-binding atopy-related autoantigen 1; allergen Hom s 4
  • Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013],
  • Function: allergen:Causes an allergic reaction in human. Binds to IgE from atopic dermatitis (AD) patients. Identified as an IgE autoantigen in atopic dermatitis (AD) patients with severe skin manifestations.,function:Induces T helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.,sequence caution:Contaminating sequence. Sequence of unknown origin in the N-terminal part.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expressed in epithelial cell line. Strongly expressed in epidermal keratinocytes and dermal endothelial cells.,
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