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SKU:YP-Ab-01027-10UL
THAP11 Monoclonal Antibody
THAP11 Monoclonal Antibody
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- Reaction species: Human
- Gene Name: THAP11
- Protein name: THAP domain-containing protein 11
- Immunogen: Purified recombinant fragment of human THAP11 expressed in E. Coli.
- Specificity: THAP11 Monoclonal Antibody detects endogenous levels of THAP11 protein.
- Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: Affinity purification
- Storage: -20°C/1 year
- Other Names: THAP11; HRIHFB2206; THAP domain-containing protein 11
- Background: The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008],
- Function: function:Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.,polymorphism:The length of the poly-Gln region is variable in the population.,similarity:Belongs to the THAP11 family.,similarity:Contains 1 THAP-type zinc finger.,subcellular location:May be regulated by shuttling of the protein between the cytoplasm and nucleus.,subunit:Interacts (via coiled coil domain) with HCFC1.,
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