• Msi1 Monoclonal Antibody
1 1

Upingbio

YP-Ab-01004-100UL

Msi1 Monoclonal Antibody

Msi1 Monoclonal Antibody

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  • Reaction species: Human
  • Gene Name: MSI1
  • Protein name: RNA-binding protein Musashi homolog 1
  • Immunogen: Purified recombinant fragment of human Msi1 expressed in E. Coli.
  • Specificity: Msi1 Monoclonal Antibody detects endogenous levels of Msi1 protein.
  • Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Storage: -20°C/1 year
  • Other Names: MSI1; RNA-binding protein Musashi homolog 1; Musashi-1
  • Background: This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008],
  • Function: domain:The first RNA recognition motif binds more strongly to RNA compared to the second one.,function:RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.,similarity:Belongs to the Musashi family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.,
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