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Upingbio

SKU:YP-Ab-00981-53UL

FoxP3 Monoclonal Antibody

FoxP3 Monoclonal Antibody

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  • Reaction species: Human;Mouse
  • Gene Name: FOXP3
  • Protein name: Forkhead box protein P3
  • Immunogen: Purified recombinant fragment of human FoxP3 expressed in E. Coli.
  • Specificity: FoxP3 Monoclonal Antibody detects endogenous levels of FoxP3 protein.
  • Composition: Purified antibody in PBS containing 0.03% sodium azide.
  • Source: Monoclonal, Mouse
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: Affinity purification
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: FOXP3; IPEX; JM2; Forkhead box protein P3; Scurfin
  • Background: The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
  • Function: disease:Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.,function:Probable transcription factor. Plays a critical role in the control of immune response.,online information:FOXP3 entry,online information:FOXP3 mutation db,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,
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