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Upingbio
SKU:YP-Ab-00977-53UL
FoxA2 Monoclonal Antibody
FoxA2 Monoclonal Antibody
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- Reaction species: Human
- Gene Name: FOXA2
- Protein name: Hepatocyte nuclear factor 3-beta
- Immunogen: Purified recombinant fragment of FoxA2 expressed in E. Coli.
- Specificity: FoxA2 Monoclonal Antibody detects endogenous levels of FoxA2 protein.
- Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
- Purification process: Affinity purification
- Storage: -20°C/1 year
- Other Names: FOXA2; HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; Forkhead box protein A2; Transcription factor 3B; TCF-3B
- Background: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008],
- Function: function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Binds TLE1.,
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