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Upingbio
SKU:YP-Ab-00955-53UL
Blimp-1 Monoclonal Antibody
Blimp-1 Monoclonal Antibody
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- Reaction species: Human;Mouse
- Gene Name: PRDM1
- Protein name: PR domain zinc finger protein 1
- Immunogen: Purified recombinant fragment of human Blimp-1 expressed in E. Coli.
- Specificity: Blimp-1 Monoclonal Antibody detects endogenous levels of Blimp-1 protein.
- Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: Affinity purification
- Storage: -20°C/1 year
- Other Names: PRDM1; BLIMP1; PR domain zinc finger protein 1; BLIMP-1; Beta-interferon gene positive regulatory domain I-binding factor; PR domain-containing protein 1; Positive regulatory domain I-binding factor 1; PRDI-BF1; PRDI-binding factor 1
- Background: This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008],
- Function: function:Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.,similarity:Contains 1 SET domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with PRMT5.,
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