• VAMP-4 Polyclonal Antibody
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Upingbio

YP-Ab-00754-100UL

VAMP-4 Polyclonal Antibody

VAMP-4 Polyclonal Antibody

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  • Gene Name: VAMP4
  • Immunogen: The antiserum was produced against synthesized peptide derived from human VAMP4. AA range:1-50
  • Specificity: VAMP-4 Polyclonal Antibody detects endogenous levels of VAMP-4 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: VAMP4; Vesicle-associated membrane protein 4; VAMP-4
  • Background: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008],
  • Function: function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.,subunit:Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,
  • Species: Human;Mouse
  • Range: IF;ELISA
  • Protein: Vesicle-associated membrane protein 4
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