• ABCB5 Monoclonal Antibody(11A2)
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Upingbio

YP-Ab-00626-53UL

ABCB5 Monoclonal Antibody(11A2)

ABCB5 Monoclonal Antibody(11A2)

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Size
  • Reaction species: Human
  • Gene Name: ABCB5
  • Protein name: ATP-binding cassette sub-family B member 5
  • Molecular weight (DA): 90kD
  • Immunogen: Synthetic Peptide of ABCB5
  • Specificity: The antibody detects endogenous ABCB5 proteins.
  • Composition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: WB: 1:2000 IF 1:200 IHC 1:50-300
  • Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: ABCB5; ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5
  • Background: ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008],
  • Function: caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,caution:Was named ABCB1 by some authors.,function:Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas.,miscellaneous:Depletion of ABCB5 by RNAi increases the sensitivity to several drugs of a subset of melanoma cells.,similarity:Belongs to the ABC transporter family.,similarity:Belongs to the ABC transporter family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.,similarity:Contains 1 ABC transmembrane type-1 domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,similarity:Contains 2 ABC transporter domains.,subunit:Component of the U11/U12 snRNPs that are part of the U12-type spliceosom
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