• SYP Monoclonal Antibody
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Upingbio

YP-Ab-00618-53UL

SYP Monoclonal Antibody

SYP Monoclonal Antibody

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  • Reaction species: Human;Rat
  • Gene Name: SYP
  • Protein name: Synaptophysin
  • Immunogen: Purified recombinant fragment of SYP expressed in E. Coli.
  • Specificity: SYP Monoclonal Antibody detects endogenous levels of SYP protein.
  • Composition: Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
  • Source: Monoclonal, Mouse
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
  • Purification process: Affinity purification
  • Storage: -20°C/1 year
  • Other Names: SYP; Synaptophysin; Major synaptic vesicle protein p38
  • Background: This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],
  • Function: domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,
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