• Beclin-1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-00587-100UL

Beclin-1 Polyclonal Antibody

Beclin-1 Polyclonal Antibody

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  • Gene Name: BECN1 GT197
  • Immunogen: Synthesized peptide derived from Beclin-1 . at AA range: 110-190
  • Specificity: Beclin-1 Polyclonal Antibody detects endogenous levels of Beclin-1
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000, ELISA 1:10000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: beclin 1, autophagy related
  • Background: beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
  • Function: function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,
  • Species: Human;Mouse;Chicken
  • Range: WB;ELISA
  • Protein: Beclin-1
  • DA: 55kD
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