• ARP Polyclonal Antibody
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Upingbio

YP-Ab-00572-100UL

ARP Polyclonal Antibody

ARP Polyclonal Antibody

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  • Gene Name: MANF
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MANF. AA range:11-60
  • Specificity: ARP Polyclonal Antibody detects endogenous levels of ARP protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: MANF; ARMET; ARP; Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET
  • Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related. [provided by RefSeq, Apr 2014],
  • Function: response to unfolded protein, response to organic substance, response to protein stimulus,
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Mesencephalic astrocyte-derived neurotrophic factor
  • DA: 20kD
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