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Upingbio
SKU:YP-Ab-00564-100UL
BNIP-3 Polyclonal Antibody
BNIP-3 Polyclonal Antibody
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- Gene Name: BNIP3
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120
- Specificity: BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: BNIP3; NIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- Background: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
- Function: function:Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.,similarity:Belongs to the NIP3 family.,subcellular location:Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope.,subunit:Homodimer. Binds to BCL2. Interacts with BNIP3L. Also can interact with adenovirus E1B 19 kDa protein or Epstein-Barr virus BHRF1.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC;IF;ELISA
- Protein: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
- DA: 22kD
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