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Upingbio
SKU:YP-Ab-00558-100UL
BAGE5 Polyclonal Antibody
BAGE5 Polyclonal Antibody
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- Gene Name: BAG5
- Immunogen: Synthesized peptide derived from BAGE5 . at AA range: 30-110
- Specificity: BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: BAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5
- Background: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- Function: function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: BAG family molecular chaperone regulator 5
- DA: 51kD
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