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SKU:YP-Ab-00528-100UL
TACC3 Polyclonal Antibody
TACC3 Polyclonal Antibody
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- Gene Name: TACC3
- Immunogen: The antiserum was produced against synthesized peptide derived from human TACC3. AA range:789-838
- Specificity: TACC3 Polyclonal Antibody detects endogenous levels of TACC3 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: TACC3; ERIC1; Transforming acidic coiled-coil-containing protein 3; ERIC-1
- Background: This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011],
- Function: function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.,induction:Up-regulated in various cancer cell lines.,similarity:Belongs to the TACC family.,subunit:Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2 (By similarity). Interacts with GCN5L2 and PCAF.,
- Species: Human;Mouse
- Range: WB;IHC;IF;ELISA
- Protein: Transforming acidic coiled-coil-containing protein 3
- DA: 80kD
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