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Upingbio

SKU:YP-Ab-00495-100UL

PMEPA1 Polyclonal Antibody

PMEPA1 Polyclonal Antibody

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  • Gene Name: PMEPA1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150
  • Specificity: PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein
  • Background: This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
  • Function: domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;ELISA
  • Protein: Transmembrane prostate androgen-induced protein
  • DA: 37kD
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