• DOC-1 Polyclonal Antibody
1 1

Upingbio

YP-Ab-00383-100UL

DOC-1 Polyclonal Antibody

DOC-1 Polyclonal Antibody

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  • Gene Name: CDK2AP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CDKAP1. AA range:51-100
  • Specificity: DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CDK2AP1; CDKAP1; DOC1; Cyclin-dependent kinase 2-associated protein 1; CDK2-associated protein 1; Deleted in oral cancer 1; DOC-1; Putative oral cancer suppressor
  • Background: cyclin dependent kinase 2 associated protein 1(CDK2AP1) Homo sapiens The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],
  • Function: similarity:Belongs to the CDK2AP family.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Cyclin-dependent kinase 2-associated protein 1
  • DA: 20kD
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