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Upingbio
SKU:YP-Ab-00323-100UL
BCL2L12 Polyclonal Antibody
BCL2L12 Polyclonal Antibody
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- Gene Name: BCL2L12
- Immunogen: Synthesized peptide derived from BCL2L12 . at AA range: 60-140
- Specificity: BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein
- Background: This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
- Function: similarity:Belongs to the Bcl-2 family.,tissue specificity:Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Bcl-2-like protein 12
- DA: 34kD
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