• ANKT Polyclonal Antibody
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Upingbio

YP-Ab-00298-100UL

ANKT Polyclonal Antibody

ANKT Polyclonal Antibody

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  • Gene Name: NUSAP1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human NUSAP1. AA range:392-441
  • Specificity: ANKT Polyclonal Antibody detects endogenous levels of ANKT protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: NUSAP1; ANKT; BM-037; Nucleolar and spindle-associated protein 1; NuSAP
  • Background: NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).[supplied by OMIM, Jun 2009],
  • Function: domain:The KEN box is required for the FZR1-dependent degradation of this protein subsequent to ubiquitination.,function:Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated. Ubiquitination by FZR1 may lead to proteasome-dependent degradation of this protein.,similarity:Belongs to the NUSAP family.,subcellular location:Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase (By similarity). Localizes to the mitotic spindle during anaphase and telophase then disappears from around the chromosomes during cytokinesis (By similarity). Localizes to multiple distinct regions of chromosomes throughout mitosis.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Nucleolar and spindle-associated protein 1
  • DA: 49kD
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