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SKU:YP-Ab-00283-100UL
TACC3 (phospho-Ser558) rabbit pAb
TACC3 (phospho-Ser558) rabbit pAb
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- Gene Name: TACC3 ERIC1
- Immunogen: Synthesized phosho peptide around human TACC3 (Ser558)
- Specificity: This antibody detects endogenous levels of Human TACC3 (phospho-Ser558)
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:1000-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
- Background: This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011],
- Function: function:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.,induction:Up-regulated in various cancer cell lines.,similarity:Belongs to the TACC family.,subunit:Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2 (By similarity). Interacts with GCN5L2 and PCAF.,
- Species: Human;Rat;Mouse;
- Range: WB
- Protein: TACC3 (Ser558)
- DA: 80kD
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