• Beclin-1 (phospho-Ser15) rabbit pAb
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Upingbio

YP-Ab-00262-100UL

Beclin-1 (phospho-Ser15) rabbit pAb

Beclin-1 (phospho-Ser15) rabbit pAb

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  • Gene Name: BECN1 GT197
  • Immunogen: Synthesized phosho peptide around human Beclin-1 (Ser15)
  • Specificity: This antibody detects endogenous levels of Human Mouse Beclin-1 (phospho-Ser15)
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)
  • Background: beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
  • Function: function:Plays a central role in autophagy (By similarity). May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.,similarity:Belongs to the beclin family.,subcellular location:Expressed in dendrites and cell bodies of cerebellar Purkinje cells.,subunit:Interacts with GOPC and GRID2. Interacts with AMBRA1. Probably forms a complex with AMBRA1 and PIK3C3 (By similarity). Interacts with BCL2 and BCL2L1.,tissue specificity:Ubiquitous.,
  • Species: Human;Mouse
  • Range: WB
  • Protein: Beclin-1 (Ser15)
  • DA: 60kD
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