YOD1 Antibody

Size

100ug

Clone Number

Aliases

DUBA-8 antibody; DUBA8 antibody; HIN-7 antibody; HIV-1-induced protease 7 antibody; HsHIN7 antibody; OTU domain containing 2 antibody; OTU domain-containing protein 2 antibody; OTU1_HUMAN antibody; OTUD2 antibody; PRO0907 antibody; RP11-164O23.1 antibody; Ubiquitin thioesterase OTU1 antibody; yod1 antibody; YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae) antibody; YOD1 OTU deubiquinating enzyme 1 homolog (yeast) antibody; YOD1 OTU deubiquinating enzyme 1; S. cerevisiae; homolog of antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q5VVQ6

Immunogen

Recombinant Human Ubiquitin thioesterase OTU1 protein (1-44AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP\\\'s axial channel. Mediates deubiquitination of \\\'Lys-27\\\'-, \\\'Lys-29\\\'- and \\\'Lys-33\\\'-linked polyubiquitin chains. Also able to hydrolyze \\\'Lys-11\\\'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

YOD1

Research Areas

Cell biology; Metabolism; Signal transduction