YAP(Phospho Ser127) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Reactivity

Human, Mouse, Rat, Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human YAP around the phosphorylation site of Ser127. AA range:93-142

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

48755

synonyms

Yorkie homolog; YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65