XRCC1 Polyclonal Antibody

Ab type

Primary antibody

Background

DNA repair protein XRCC1 encoded by XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human XRCC1. AA range:517-566

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

69526

synonyms

XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1