WWOX Antibody

Size

100ug

Clone Number

Aliases

5330426P09Rik antibody; 9030416C10Rik antibody; Aberrant WW domain-containing oxidoreductase antibody; D16S432E antibody; EC 1.1.1.- antibody; EIEE28 antibody; FOR antibody; FRA16D antibody; Fragile site FRA16D oxidoreductase antibody; Fragile site FRA16D Oxireductase antibody; HHCMA56 antibody; MGC55975 antibody; PRO0128 antibody; Putative oxidoreductase antibody; SCAR12 antibody; SDR41C1 antibody; Short chain dehydrogenase/reductase family 41C, member 1 antibody; WOX1 antibody; WW domain containing oxidoreductase antibody; WW domain-containing oxidoreductase antibody; WW domain-containing protein WWOX antibody; wwox antibody; WWOX_HUMAN antibody; zgc:55975 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NZC7

Immunogen

Recombinant Human WW domain-containing oxidoreductase protein (1-180AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200, IP:1:200-1:2000

Background

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

WWOX

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology