WISP1 Antibody

Size

100ug

Clone Number

Aliases

CCN4 antibody; WISP1 antibody; CCN family member 4 antibody; WNT1-inducible-signaling pathway protein 1 antibody; WISP-1 antibody; Wnt-1-induced secreted protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O95388

Immunogen

Recombinant Human WNT1-inducible-signaling pathway protein 1 protein (130-251AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

WISP1

Research Areas

Epigenetics and Nuclear Signaling; Stem cells