WDR59 Antibody

Size

100ul

Clone Number

Aliases

WDR59 antibody; KIAA1923 antibody; FP977 antibody; GATOR complex protein WDR59 antibody; WD repeat-containing protein 59 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q6PJI9

Immunogen

Recombinant Human GATOR complex protein WDR59 protein (619-862AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200

Background

As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

WDR59

Research Areas

Cell biology