WDR5 Antibody

Size

100ul

Clone Number

Aliases

2410008O07Rik antibody; AA408785 antibody; AA960360 antibody; BIG 3 antibody; Big antibody; BIG3 antibody; BMP2 induced 3 kb gene protein antibody; BMP2 induced gene; 3-KB antibody; BMP2-induced 3-kb gene protein antibody; MGC114572 antibody; OTTHUMP00000162494 antibody; SWD 3 antibody; SWD3 antibody; SWD3 Set1c WD40 repeat protein homolog antibody; WD repeat containing protein 5 antibody; WD repeat domain 5 antibody; WD repeat protein 5 antibody; WD repeat-containing protein 5 antibody; WD repeat-containing protein BIG-3 antibody; WDR 5 antibody; Wdr5 antibody; WDR5_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P61964

Immunogen

Recombinant Human WD repeat-containing protein 5 protein (1-334AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at \\\'Lys-4\\\'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at \\\'Lys-4\\\' of histone H3. H3 \\\'Lys-4\\\' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

WDR5

Research Areas

Epigenetics and Nuclear Signaling