WARS Antibody

Size

100ul

Clone Number

Aliases

Gamma 2 antibody; GAMMA-2 antibody; Gamma2 antibody; hWRS antibody; IFI 53 antibody; IFI53 antibody; IFP 53 antibody; IFP53 antibody; Interferon induced protein 53 antibody; Interferon-induced protein 53 antibody; SYWC_HUMAN antibody; T2-TrpRS antibody; TrpRS antibody; Tryptophan tRNA ligase; cytoplasmic antibody; Tryptophan tRNA ligase 1 cytoplasmic antibody; Tryptophan tRNA ligase antibody; Tryptophan--tRNA ligase antibody; Tryptophanyl tRNA synthetase antibody; Tryptophanyl tRNA synthetase cytoplasmic antibody; WARS antibody; WARS protein antibody; WRS antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P23381

Immunogen

Recombinant Human Tryptophan--tRNA ligase, cytoplasmic protein (27-99AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

WARS

Research Areas

Epigenetics and Nuclear Signaling