VRK3 Polyclonal Antibody

Ab type

Primary antibody

Background

VRK3 (vaccinia related kinase 3) encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, VRK3 has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. VRK3 is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human VRK3.

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

52881

synonyms

VRK3; Inactive serine/threonine-protein kinase VRK3; Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3