VPS51 Antibody, HRP conjugated

Size

100ul

Clone Number

Aliases

ANG2 antibody; ANG3 antibody; Another new gene 2 protein antibody; C11orf3 antibody; chromosome 11 open reading frame 2 antibody; Fat free homolog antibody; ffr antibody; FFR_HUMAN antibody; FFR|FLJ13879 antibody; FLJ36472 antibody; Protein fat-free homolog antibody; Vacuolar protein sorting 51 homolog antibody; VPS51 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9UID3

Immunogen

Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

VPS51

Research Areas

Signal transduction