VPS25 Antibody

Size

100ug

Clone Number

Aliases

Dermal papilla derived protein 9 antibody; Dermal papilla-derived protein 9 antibody; DERP9 antibody; EAP20 antibody; ELL associated protein of 20 kDa antibody; ELL-associated protein of 20 kDa antibody; ESCRT-II complex subunit VPS25 antibody; FAP20 antibody; HGNC:28122 antibody; hVps25 antibody; MGC10540 antibody; Vacuolar protein sorting 25 homolog (S. cerevisiae) antibody; Vacuolar protein sorting associated protein 25 antibody; Vacuolar protein-sorting-associated protein 25 antibody; VPS25 antibody; VPS25_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BRG1

Immunogen

Recombinant Human Vacuolar protein-sorting-associated protein 25 protein (1-176AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

VPS25

Research Areas

Signal transduction