Vimentin(Phospho-Tyr38) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents| along with microtubules and actin microfilaments| make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape| integrity of the cytoplasm| and stabilizing cytoskeletal interactions. It is also involved in the immune response| and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment| migration| and cell signaling. Mutations in this gene causes a dominant| pulverulent cataract.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

51260

synonyms

vimentin; VIM