VCAM1 Monoclonal Antibody

Size

Clone Number

Aliases

CD106; MGC99561; INCAM-100; DKFZp779G2333; VCAM1

Immunogen Species

Human

UniProt ID

P19320

Immunogen

Purified recombinant fragment of human VCAM1 expressed in E. Coli

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500

Background

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

VCAM1

Research Areas

Neuroscience?Cancer?Cardiovascular;Signal transduction?Stem cells