Vav3 Polyclonal Antibody

Ab type

Primary antibody

Background

VAV3 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human VAV3. AA range:139-188

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

97776

synonyms

VAV3; Guanine nucleotide exchange factor VAV3; VAV-3