Vav3(Phospho Tyr173) Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

97776

synonyms

Guanine nucleotide exchange factor VAV3; VAV3; Guanine nucleotide exchange factor VAV3; VAV-3