VATE1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a component of vacuolar ATPase (V-ATPase)| a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting| zymogen activation| receptor-mediated endocytosis| and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A| three B| and two G subunits| as well as a C| D| E| F| and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants| encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human VATE1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

24860

synonyms

VATE1