Skip to product information
1 of 1

NSJ Bioreagents

SKU:V9635SAF-100UG

VLDLR Antibody / VLDL Receptor

VLDLR Antibody / VLDL Receptor

Regular price $539.00 USD
Regular price Sale price $539.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
Host Animal

VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

View full details