USP9X Antibody

Size

100ug

Clone Number

Aliases

Deubiquitinating enzyme FAF X antibody; Deubiquitinating enzyme FAF-X antibody; DFFRX antibody; Drosophila fat facets related X linked antibody; FAF antibody; Fafl antibody; Fam antibody; Fat facets homolog antibody; Fat facets in mammals antibody; Fat facets protein related X linked antibody; Fat facets protein related, X-linked antibody; Fat facets protein-related antibody; hFAM antibody; MRX99 antibody; Probable ubiquitin carboxyl terminal hydrolase FAF X antibody; Probable ubiquitin carboxyl-terminal hydrolase FAF-X antibody; Ubiquitin carboxyl-terminal hydrolase FAM antibody; Ubiquitin specific peptidase 9 X linked antibody; Ubiquitin specific peptidase 9, X-linked antibody; Ubiquitin specific processing protease FAF X antibody; Ubiquitin specific protease 9 X chromosome antibody; Ubiquitin thioesterase FAF X antibody; Ubiquitin thiolesterase FAF X antibody; Ubiquitin thiolesterase FAF-X antibody; Ubiquitin-specific protease 9 antibody; Ubiquitin-specific-processing protease FAF-X antibody; USP9 (gene name) antibody; Usp9x antibody; USP9X_HUMAN antibody; Uubiquitin specific protease 9, X chromosome (fat facets like Drosophila) antibody; X chromosome antibody; X-linked antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q93008

Immunogen

Recombinant Human Probable ubiquitin carboxyl-terminal hydrolase FAF-X protein (2360-2484AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both \\\'Lys-29\\\'- and \\\'Lys-33\\\'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

USP9X

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cell biology