USP4 Antibody

Size

100ug

Clone Number

Aliases

Deubiquitinating enzyme 4 antibody; MGC149848 antibody; MGC149849 antibody; Proto oncogene antibody; Protooncogene antibody; Ubiquitin carboxyl terminal hydrolase 4 antibody; Ubiquitin carboxyl-terminal hydrolase 4 antibody; Ubiquitin specific peptidase 4 (proto oncogene) antibody; Ubiquitin specific peptidase 4 (protooncogene) antibody; Ubiquitin specific peptidase 4 antibody; Ubiquitin specific processing protease 4 antibody; Ubiquitin specific protease 4 (proto oncogene) antibody; Ubiquitin specific protease 4 (protooncogene) antibody; Ubiquitin specific protease 4 antibody; Ubiquitin specific protease proto oncogene antibody; Ubiquitin specific protease protooncogene antibody; Ubiquitin thioesterase 4 antibody; Ubiquitin thiolesterase 4 antibody; Ubiquitin-specific-processing protease 4 antibody; Ubiquitous nuclear protein homolog antibody; UBP4_HUMAN antibody; UNP antibody; UNPH antibody; USP 4 antibody; USP4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13107

Immunogen

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 4 protein (632-810AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:200

Background

Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3. This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6.U5 snRNP. May also play a role in the regulation of quality control in the ER.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

USP4

Research Areas

Epigenetics and Nuclear Signaling; Cell biology