USP3 Antibody

Size

100ug

Clone Number

Aliases

Deubiquitinating enzyme 3 antibody; EC 3.1.2.15 antibody; SIH003 antibody; Ubiquitin carboxyl-terminal hydrolase 3 antibody; Ubiquitin specific peptidase 3 antibody; Ubiquitin specific processing protease 3 antibody; Ubiquitin Specific Protease 3 antibody; Ubiquitin thioesterase 3 antibody; Ubiquitin thiolesterase 3 antibody; Ubiquitin-specific-processing protease 3 antibody; UBP antibody; UBP3_HUMAN antibody; Usp3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9Y6I4

Immunogen

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 3 protein (201-500AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

USP3

Research Areas

Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Signal transduction